In vitro activities of cefotaxime and moxalactam (LY127935) against Haemophilus influenzae.
نویسندگان
چکیده
The in vitro activities of two new beta-lactam antibiotics, cefotaxime and moxalactam (LY127935), were compared with those of cefamandole, cefoxitin, cefuroxime, and ampicillin against both beta-lactamase-producing and non-beta-lactamase-producing isolates of Haemophilus influenzae. Both cefotaxime and LY127935 were highly active against all isolates irrespective of beta-lactamase production.
منابع مشابه
Effect of inoculum size and beta-lactamase production on in vitro activity of new cephalosporins against Haemophilus species.
Sixty-three strains of Haemophilus species, 38 of which were beta-lactamase producers (37 H. influenzae type b, 1 H. parainfluenzae) and 25 of which were beta-lactamase negative (20 H. influenzae, 5 H. parainfluenzae), were tested for susceptibility to cefoxitin, moxalactam (LY127935) (Lilly), cefsulodin (CGP 7174 E, Ciba), and cefoperazone (T 1551, Pfizer). Cefsulodin was relatively inactive a...
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 17 3 شماره
صفحات -
تاریخ انتشار 1980